Boiling point :695.1±55.0 °C(Predicted)density ;1.428±0.06 g/cm3(Predicted)pka:10.70±0.70(Predicted)MF: C25H25Cl2FN6O3MW:547.41!!spec!!fea.Boiling point :695.1±55.0 °C(Predic.pka:10.70±0.70(Pre ... ...
Fine chemical ...
Melting point :>133°C (dec.)density :1.37±0.1 g/cm3(Predicted)storage temp. :Refrigeratorsolubility : Soluble in DMSO (up to at least 25 mg/ml)form :solidpka: 11.47±0.70(Predicted)color :YellowStab ... ...
Melting point :>203°C (dec.)Boiling point :781.8±70.0 °C(Predicted)density : 1.31±0.1 g/cm3(Predicted)storage temp. :-20°Csolubility :Soluble in DMSO (1 mg/ml with warming)pka: 8.14±0.42(Predict ... ...
Melting point:274-276°CBoiling point :722.5±60.0 °C(Predicted)density:1.28storage temp. : -20°form :solidcolor : White!!spec!!fea.MF:C30H34N4O2.MW:482.62.EINECS:821-541-6 ...
Melting point :153-158°CBoiling point :715.0±60.0 °C(Predicted)density :1.34storage temp. :-20°Csolubility :Soluble in DMSO ( up to at least 25 mg/ml)pka:4.09±0.30(Predicted)form : solidcolor ... ...
Ceritinib is a new ALK gene inhibitor (ALKi) developed by Novartis Pharmaceuticals; its commercial name is Zykadia, and its previous code was LDK378. It was approved by the FDA for sale on April 29, 2 ... ...
Melting point : 184-187°CBoiling point : 675.0±55.0 °C(Predicted)density :1.42±0.1 g/cm3(Predicted)storage temp. :Hygroscopic, -20°C Freezer, Under inert atmospheresolubility :Chlorofor ... ...
Potent inhibitor of c-MET and anaplastic lymphoma kinase (ALK) (cell IC50 values are 8.0 and 20 nM respectively). Selective for c-MET and ALK against >120 different kinases. Displays antitumor efficac ... ...
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